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mouse anti-human braf v600e monoclonal antibody (clone ve1)  (Spring Bioscience)

 
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    Structured Review

    Spring Bioscience mouse anti-human braf v600e monoclonal antibody (clone ve1)
    Lymphocyte biomarkers and distribution by BRAF mutation status
    Mouse Anti Human Braf V600e Monoclonal Antibody (Clone Ve1), supplied by Spring Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti-human+braf+v600e+(clone+ve1)+monoclonal+antibody/braf+v600e+antibody/pmc07801318-75-1-6
    Average 90 stars, based on 1 article reviews
    mouse anti-human braf v600e monoclonal antibody (clone ve1) - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy"

    Article Title: Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy

    Journal: Annals of Surgical Oncology

    doi: 10.1245/s10434-020-08713-1

    Lymphocyte biomarkers and distribution by BRAF mutation status
    Figure Legend Snippet: Lymphocyte biomarkers and distribution by BRAF mutation status

    Techniques Used: Mutagenesis

    Clinical response to DPCP correlated with OS by biomarker status
    Figure Legend Snippet: Clinical response to DPCP correlated with OS by biomarker status

    Techniques Used: Biomarker Discovery

    Related Articles

    Mutagenesis:

    Article Title: BRAF V600E Mutations Occur in a Subset of Glomus Tumors, and Are Associated With Malignant Histologic Characteristics
    Article Snippet: Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body.. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior.. We recently encountered a malignant glomus tumor with BRAF V600E mutation.

    Expressing:

    Article Title: BRAF V600E Mutations Occur in a Subset of Glomus Tumors, and Are Associated With Malignant Histologic Characteristics
    Article Snippet: Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body.. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior.. We recently encountered a malignant glomus tumor with BRAF V600E mutation.

    Immunohistochemistry:

    Article Title: BRAF V600E Mutations Occur in a Subset of Glomus Tumors, and Are Associated With Malignant Histologic Characteristics
    Article Snippet: Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body.. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior.. We recently encountered a malignant glomus tumor with BRAF V600E mutation.

    other:

    Article Title: Comparison of Molecular Methods and BRAF Immunohistochemistry (VE1 Clone) for the Detection of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Meta-Analysis
    Article Snippet: The majority of the studies used the anti-human BRAF V600E (clone VE1) monoclonal antibody by Spring Bioscience (Spring Bioscience Pleasanton, CA, USA) [ 11 , 13 – 15 , 18 , 21 , 25 , 26 , 28 – 30 , 32 , 39 , 40 ] or Ventana medical systems (Ventana Medical Systems, Roche Diagnostics Indianapolis, IN, USA) [ 12 , 17 , 19 , 20 , 22 , 33 – 35 ].

    Article Title: Quantitative analysis of wild-type and V600E mutant BRAF proteins in colorectal carcinoma using immunoenrichment and targeted mass spectrometry.
    Article Snippet: Immunoenrichment coupled with MRM or SIM-AIMS assay was evaluated for quantifying WT and V600E mutant BRAF proteins in CRC.. Both assays could successfully detect/ quantify both targets in a CRC cell line and CRC tissue samples.. Both targets could be quantified at the level of sub ng/mg protein

    Article Title: Long-Term Extracorporeal Membrane Oxygenation as Bridging Strategies to Lung Transplantation in Rapidly Devastating Isolated Langerhans Cell Histiocytosis.
    Article Snippet: Isolated pulmonary involvement in pediatric Langerhans cell histiocytosis (LCH) is extremely rare.. While the multisystem-LCH course varies from spontaneous remission to rapid deterioration with lethal outcome, single system involvement is generally associated with favorable prognosis.. A child with isolated pulmonary LCH had an extremely rapid progression leading to respiratory failure, despite treatment with prednisone and vinblastine.

    Article Title: BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin.
    Article Snippet: BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin Jau-Yu Liau MD, Jia-Huei Tsai MD, Wen-Chang Huang MD, Jui Lan MD, Jin-Bon Hong MD, Chang-Tsu Yuan MD PII: S0046-8177(17)30467-7 DOI: doi: 10.1016/j.humpath.2017.12.002 Reference: YHUPA 4419 To appear in: Human Pathology Received date: 26 September 2017 Revised date: 17 November 2017 Accepted date: 1 December 2017 Please cite this article as: Liau Jau-Yu, Tsai Jia-Huei, Huang Wen-Chang, Lan Jui, Hong Jin-Bon, Yuan Chang-Tsu, BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin, Human Pathology (2017), doi: 10.1016/j.humpath.2017.12.002 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form.

    Article Title: BRAF V600E Inhibitor (Vemurafenib) for BRAF V600E Mutated Low Grade Gliomas
    Article Snippet: As for immunohistochemistry, 3-micron paraffin embedded sections were dehydrated, pretreated with avidin block for 15' and biotin block for 15', then incubated with BSA for 30' and incubated with mouse anti-human BRAF V600E monoclonal antibody (clone VE1, Spring Bioscience) at room temperature for 60' (dilution 1:50, PT-link antigen retrival at high pH).

    Article Title: The clinicopathological features of ganglioglioma with CD34 expression and BRAF mutation in patients with epilepsy
    Article Snippet: Immunohistochemical staining was performed with the following primary antibodies: anti-BRAF V600E (Spring Bioscience, monoclonal, clone VE1, 1:50), glial fibrillary acidic protein (GFAP; Dako, 1:1000), neuronal nuclear antigen (NeuN; Chemicon, 1:2000), neurofilament (NF; Zymed, 1:100), synaptophysin (Biogenics, 1:50), oligodendrocyte transcription factor 2 (Olig-2; Immuno-Biological Laboratories, 1:500), epithelial cell membrane antigen (EMA; Zymed, 1:100), Ki-67 (MIB-1; OriGene, monoclonal, clone UMAB107, 1:200), p53 (Zymed, 1:100), CD68 (Bio-Rad, 1:500), CD34 (Zymed, monoclonal, clone QBEnd 10, 1:50), isocitrate dehydrogenase (IDH1/2; Zymed, 1:1000).

    Article Title: Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy
    Article Snippet: For BRAF V600E IHC, Pleasanton, CA Spring Bioscience mouse anti-human BRAF V600E monoclonal antibody (Clone VE1) was used at a dilution of 1:200 run on a routine long program.



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    Spring Bioscience mouse anti-human braf v600e monoclonal antibody (clone ve1)
    Lymphocyte biomarkers and distribution by BRAF mutation status
    Mouse Anti Human Braf V600e Monoclonal Antibody (Clone Ve1), supplied by Spring Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti-human+braf+v600e+(clone+ve1)+monoclonal+antibody/braf+v600e+antibody/pmc07801318-75-1-6
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    Spring Bioscience anti-human braf v600e (clone ve1) monoclonal antibody
    Papillary thyroid carcinoma, classic type (a) showing diffuse cytoplasmic <t>VE1</t> expression with moderate intensity (b); Papillary thyroid carcinoma, invasive follicular variant (c) showing negative VE1 immunostain (d). Evaluation of VE1 immunostain in papillary thyroid carcinoma at low power (e) may be deceptive. Higher power examination confirms diffuse but weak VE1 positivity (f) in a case with confirmed BRAF <t>V600E</t> mutation by next generation sequencing (unpublished data). These examples utilized prediluted Roche Ventana VE1 monoclonal antibody (Indianapolis, IN, USA) on the Leica Bond Refine System (Buffalo Grove, IL, USA) at 60 min incubation time
    Anti Human Braf V600e (Clone Ve1) Monoclonal Antibody, supplied by Spring Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Spring Bioscience mouse monoclonal anti-human braf v600e antibody clone ve1
    Papillary thyroid carcinoma, classic type (a) showing diffuse cytoplasmic <t>VE1</t> expression with moderate intensity (b); Papillary thyroid carcinoma, invasive follicular variant (c) showing negative VE1 immunostain (d). Evaluation of VE1 immunostain in papillary thyroid carcinoma at low power (e) may be deceptive. Higher power examination confirms diffuse but weak VE1 positivity (f) in a case with confirmed BRAF <t>V600E</t> mutation by next generation sequencing (unpublished data). These examples utilized prediluted Roche Ventana VE1 monoclonal antibody (Indianapolis, IN, USA) on the Leica Bond Refine System (Buffalo Grove, IL, USA) at 60 min incubation time
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    Papillary thyroid carcinoma, classic type (a) showing diffuse cytoplasmic <t>VE1</t> expression with moderate intensity (b); Papillary thyroid carcinoma, invasive follicular variant (c) showing negative VE1 immunostain (d). Evaluation of VE1 immunostain in papillary thyroid carcinoma at low power (e) may be deceptive. Higher power examination confirms diffuse but weak VE1 positivity (f) in a case with confirmed BRAF <t>V600E</t> mutation by next generation sequencing (unpublished data). These examples utilized prediluted Roche Ventana VE1 monoclonal antibody (Indianapolis, IN, USA) on the Leica Bond Refine System (Buffalo Grove, IL, USA) at 60 min incubation time
    Diagnostic Kit Of Moues Anti Human Braf, V600e Monoclonal Antibody Clone Ve1, supplied by Spring Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Clinical-pathological characteristics of patients and BRAF <t> V600E </t> immunostain intensity.
    Mouse Anti Human Braf V600e Monoclonal Antibody Clone Ve1, supplied by Spring Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Clinical-pathological characteristics of patients and BRAF <t> V600E </t> immunostain intensity.
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    Clinical-pathological characteristics of patients and BRAF <t> V600E </t> immunostain intensity.
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    Image Search Results


    Lymphocyte biomarkers and distribution by BRAF mutation status

    Journal: Annals of Surgical Oncology

    Article Title: Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy

    doi: 10.1245/s10434-020-08713-1

    Figure Lengend Snippet: Lymphocyte biomarkers and distribution by BRAF mutation status

    Article Snippet: For BRAF V600E IHC, Pleasanton, CA Spring Bioscience mouse anti-human BRAF V600E monoclonal antibody (Clone VE1) was used at a dilution of 1:200 run on a routine long program.

    Techniques: Mutagenesis

    Clinical response to DPCP correlated with OS by biomarker status

    Journal: Annals of Surgical Oncology

    Article Title: Quantitative and Spatial Analysis of CD8+/PD-1 Tumor-Infiltrating Lymphocytes as a Predictive Biomarker for Clinical Response of Melanoma In-Transit Metastases to Topical Immunotherapy

    doi: 10.1245/s10434-020-08713-1

    Figure Lengend Snippet: Clinical response to DPCP correlated with OS by biomarker status

    Article Snippet: For BRAF V600E IHC, Pleasanton, CA Spring Bioscience mouse anti-human BRAF V600E monoclonal antibody (Clone VE1) was used at a dilution of 1:200 run on a routine long program.

    Techniques: Biomarker Discovery

    Papillary thyroid carcinoma, classic type (a) showing diffuse cytoplasmic VE1 expression with moderate intensity (b); Papillary thyroid carcinoma, invasive follicular variant (c) showing negative VE1 immunostain (d). Evaluation of VE1 immunostain in papillary thyroid carcinoma at low power (e) may be deceptive. Higher power examination confirms diffuse but weak VE1 positivity (f) in a case with confirmed BRAF V600E mutation by next generation sequencing (unpublished data). These examples utilized prediluted Roche Ventana VE1 monoclonal antibody (Indianapolis, IN, USA) on the Leica Bond Refine System (Buffalo Grove, IL, USA) at 60 min incubation time

    Journal: Head and Neck Pathology

    Article Title: Comparison of Molecular Methods and BRAF Immunohistochemistry (VE1 Clone) for the Detection of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Meta-Analysis

    doi: 10.1007/s12105-020-01166-8

    Figure Lengend Snippet: Papillary thyroid carcinoma, classic type (a) showing diffuse cytoplasmic VE1 expression with moderate intensity (b); Papillary thyroid carcinoma, invasive follicular variant (c) showing negative VE1 immunostain (d). Evaluation of VE1 immunostain in papillary thyroid carcinoma at low power (e) may be deceptive. Higher power examination confirms diffuse but weak VE1 positivity (f) in a case with confirmed BRAF V600E mutation by next generation sequencing (unpublished data). These examples utilized prediluted Roche Ventana VE1 monoclonal antibody (Indianapolis, IN, USA) on the Leica Bond Refine System (Buffalo Grove, IL, USA) at 60 min incubation time

    Article Snippet: The majority of the studies used the anti-human BRAF V600E (clone VE1) monoclonal antibody by Spring Bioscience (Spring Bioscience Pleasanton, CA, USA) [ 11 , 13 – 15 , 18 , 21 , 25 , 26 , 28 – 30 , 32 , 39 , 40 ] or Ventana medical systems (Ventana Medical Systems, Roche Diagnostics Indianapolis, IN, USA) [ 12 , 17 , 19 , 20 , 22 , 33 – 35 ].

    Techniques: Expressing, Variant Assay, Mutagenesis, Next-Generation Sequencing, Incubation

    Clinical-pathological characteristics of patients and BRAF  V600E  immunostain intensity.

    Journal: Frontiers in Oncology

    Article Title: BRAF V600E Inhibitor (Vemurafenib) for BRAF V600E Mutated Low Grade Gliomas

    doi: 10.3389/fonc.2018.00526

    Figure Lengend Snippet: Clinical-pathological characteristics of patients and BRAF V600E immunostain intensity.

    Article Snippet: As for immunohistochemistry, 3-micron paraffin embedded sections were dehydrated, pretreated with avidin block for 15' and biotin block for 15', then incubated with BSA for 30' and incubated with mouse anti-human BRAF V600E monoclonal antibody (clone VE1, Spring Bioscience) at room temperature for 60' (dilution 1:50, PT-link antigen retrival at high pH).

    Techniques: Sequencing